Skype:

See below screenshot for configurations on how to use Magic Camera on Skype.

1) In Skype, click tools menu, select option command. Find video settings page and select MagicCamera Capture(User Mode) as your webcam source.
(Note: If you can not see MagicCamera Capture(User Mode) listed on Skype video settings, probably your installation of Magic Camera is broken, please try to reinstall Magic Camera.)

2) Start Magic Camera's main program and click the Capture Camera task button. Then select your real webcam as Magic Camera's input. Now you can add video effects as you like.  

Windows Live Messenger:

In Live Messenger, click 'tools menu->Audio and Video setup', then following the wizard and select 'magic camera capture(user mode)' as the default webcam. 

Yahoo Messenger:

In Yahoo Messenger, on top toolbar > messenger > my webcam - this will launch the warning panel > ok > webcam is launched onto your screen - what you see is how your contact will view you. > File menu > Preferences > Webcam Broadcast > Camera Source. Then select 'Magic Camera Capture(user mode)' as the default webcam. 

Paltalk:

ooVoo:

QQ:

Flash Based:

For example, BlogTV.com, Read Here.

AIM:

Read Here.